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human FXR2 shRNA silencing Adenovirus

Name 
Ad-h-FXR2-shRNA
Cat No 
shADV-209438
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human FXR2.

shADV-209438
Ad-h-FXR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FXR2 (FMR1 autosomal homolog 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FMR1L2; fragile X mental retardation syndrome-related protein 2; fragile X mental retardation, autosomal homolog 2; fragile X-mental retardation 1-like 2; FXR2P
Description (eCommerce)
FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. FXR2 may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome [taken from NCBI Entrez Gene (Gene ID: 8087)].
Description (Vector)
FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.
Gene ID
9513
Gene Name (eCommerce)
FMR1 autosomal homolog 2
Gene Name (Vector)
FMR1 autosomal homolog 2
Gene Symbol
FXR2
HGNC ID
HGNC:4024
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2022
ORF Size (bp)
2022 bp
Protein Name (eCommerce)
Fragile X mental retardation syndrome-related protein 2
RefSeq ID
NM_004860
RefSeq Synonyms
NM_004860, BC067272, BC051907, BC020090,
Research Areas
Apoptosis,Immunology,Neurobiology,RNA Binding,RNA Transport
Research Areas (Faceted)
cell_biology,genetics,immunology,neurobiology,transcription_translation
Species
human
Target Sentence
FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. FXR2 may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome [taken from NCBI Entrez Gene (Gene ID: 8087)].
UniGene ID
Hs.52788
UniProt ID (eCommerce)
P51116

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.