human FST shRNA silencing Adenovirus

Name
Ad-h-FST-shRNA

Cat No
shADV-209350

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human FST.

shADV-209350

Ad-h-FST-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FST (follistatin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Description (Vector)

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.

Gene ID

10468

Gene Name (Vector)

follistatin

Gene Symbol

FST

HGNC ID

HGNC:3971

ORF Size (aa)

1035

ORF Size (bp)

1035 bp

RefSeq ID

NM_006350

RefSeq Synonyms

NM_013409, NM_006350, BC004107,

Species

human

UniGene ID

Hs.9914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.