human FIG4 shRNA silencing Adenovirus

Name 
Ad-h-FIG4-shRNA
Cat No 
shADV-209027
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FIG4.

shADV-209027
Ad-h-FIG4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FIG4 (FIG4 phosphoinositide 5-phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ALS11; BTOP; CMT4J; dJ249I4.1; KIAA0274; SAC3; YVS
Description (Vector)
FIG4 belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Gene ID
9896
Gene Name (Vector)
FIG4 phosphoinositide 5-phosphatase
Gene Symbol
FIG4
HGNC ID
HGNC:16873
ORF Size (aa)
2724
ORF Size (bp)
2724 bp
RefSeq ID
NM_014845
RefSeq Synonyms
NM_014845, BC041338,
Species
human
UniGene ID
Hs.529959

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.