human FGR shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FGR.
shADV-209005
Ad-h-FGR-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FGR (FGR proto-oncogene, Src family tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
c-fgr; c-src2; p55-Fgr; p55c-fgr; p58-Fgr; p58c-fgr; SRC2
Description (Vector)
FGR is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
2268
Gene Name (Vector)
FGR proto-oncogene, Src family tyrosine kinase
Gene Symbol
FGR
HGNC ID
HGNC:3697
ORF Size (aa)
1590
ORF Size (bp)
1590 bp
RefSeq ID
NM_005248
RefSeq Synonyms
NM_005248, NM_001042747, NM_001042729, BC064382,
Species
human
UniGene ID
Hs.1422
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.