human FCN3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FCN3.
shADV-208875
Ad-h-FCN3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FCN3 (ficolin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FCNH; HAKA1
Description (Vector)
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Gene ID
8547
Gene Name (Vector)
ficolin 3
Gene Symbol
FCN3
HGNC ID
HGNC:3625
ORF Size (aa)
867
ORF Size (bp)
867 bp
RefSeq ID
NM_003665
RefSeq Synonyms
NM_173452, NM_003665, BC020731,
Species
human
UniGene ID
Hs.333383
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.