human FBN3 shRNA silencing Adenovirus

Name 
Ad-h-FBN3-shRNA
Cat No 
shADV-208742
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human FBN3.

shADV-208742
Ad-h-FBN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FBN3 (fibrillin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
FBN3 encodes a protein that belongs to the fibrillin gene family. Fibrillins are extracellular matrix molecules that assemble into microfibrils in many connective tissues. FBN3 is most highly expressed in fetal tissues and its protein product is localized to extracellular microfibrils of developing skeletal elements, skin, lung, kidney, and skeletal muscle. FBN3 is potentially involved in Weill-Marchesani syndrome. While several transcript variants may exist for this gene, their full-length natures have not been described to date.
Gene ID
84467
Gene Name (Vector)
fibrillin 3
Gene Symbol
FBN3
HGNC ID
HGNC:18794
ORF Size (aa)
8430
ORF Size (bp)
8430 bp
RefSeq ID
NM_032447
RefSeq Synonyms
NM_032447, NM_001321431, BC153882,
Species
human
UniGene ID
Hs.370362

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.