human FA2H shRNA silencing Adenovirus

Name 
Ad-h-FA2H-shRNA
Cat No 
shADV-208239
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human FA2H.

shADV-208239
Ad-h-FA2H-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FA2H (fatty acid 2-hydroxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FAAH; FAH1; FAXDC1; SCS7; SPG35
Description (Vector)
FA2H encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.
Gene ID
79152
Gene Name (Vector)
fatty acid 2-hydroxylase
Gene Symbol
FA2H
HGNC ID
HGNC:21197
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_024306
RefSeq Synonyms
NM_024306, BC017049, BC010453, BC004263, BC002679,
Species
human
UniGene ID
Hs.461329

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.