human EVC2 shRNA silencing Adenovirus

Name 
Ad-h-EVC2-shRNA
Cat No 
shADV-208153
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human EVC2.

shADV-208153
Ad-h-EVC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EVC2 (EvC ciliary complex subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LBN; WAD
Description (Vector)
EVC2 encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants.
Gene ID
132884
Gene Name (Vector)
EvC ciliary complex subunit 2
Gene Symbol
EVC2
HGNC ID
HGNC:19747
ORF Size (aa)
3684
ORF Size (bp)
3684 bp
RefSeq ID
NM_147127
RefSeq Synonyms
NM_147127, NM_001166136, BC111455,
Species
human
UniGene ID
Hs.87306

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.