human ESR2 shRNA silencing Adenovirus

Name 
Ad-h-ESR2-shRNA
Cat No 
shADV-208116
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ESR2.

shADV-208116
Ad-h-ESR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ESR2 (estrogen receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2
Description (Vector)
ESR2 encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Gene ID
2100
Gene Name (Vector)
estrogen receptor 2
Gene Symbol
ESR2
HGNC ID
HGNC:3468
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_001437
RefSeq Synonyms
NM_001437, NM_001291723, NM_001291712, NM_001271877, NM_001271876, NM_001214903, NM_001214902, NM_001040276, NM_001040275, BC024181,
Species
human
UniGene ID
Hs.660607

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.