human EPOR shRNA silencing Adenovirus

Name 
Ad-h-EPOR-shRNA
Cat No 
shADV-208018
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human EPOR.

shADV-208018
Ad-h-EPOR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EPOR (erythropoietin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EPO-R
Description (Vector)
EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Gene ID
2057
Gene Name (Vector)
erythropoietin receptor
Gene Symbol
EPOR
HGNC ID
HGNC:3416
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
RefSeq ID
NM_000121
RefSeq Synonyms
NM_000121, BC112153,
Species
human
UniGene ID
Hs.631624

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.