human EME1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EME1.
shADV-207872
Ad-h-EME1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EME1 (essential meiotic structure-specific endonuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MMS4L; SLX2A
Description (Vector)
EME1 encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
Gene ID
146956
Gene Name (Vector)
essential meiotic structure-specific endonuclease 1
Gene Symbol
EME1
HGNC ID
HGNC:24965
ORF Size (aa)
1752
ORF Size (bp)
1752 bp
RefSeq ID
NM_152463
RefSeq Synonyms
NM_152463, NM_001166131, BC016470,
Species
human
UniGene ID
Hs.514330
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.