human EDARADD shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EDARADD.
shADV-207553
Ad-h-EDARADD-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EDARADD (EDAR associated death domain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ECTD11A; ECTD11B; ED3; EDA3
Description (Vector)
EDARADD was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Gene ID
128178
Gene Name (Vector)
EDAR associated death domain
Gene Symbol
EDARADD
HGNC ID
HGNC:14341
ORF Size (aa)
648
ORF Size (bp)
648 bp
RefSeq ID
NM_080738
RefSeq Synonyms
NM_145861, NM_080738, BC128082, BC046928,
Species
human
UniGene ID
Hs.352224
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.