human ECH1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ECH1.
shADV-207530
Ad-h-ECH1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ECH1 (enoyl-CoA hydratase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPXEL
Description (Vector)
ECH1 encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Gene ID
1891
Gene Name (Vector)
enoyl-CoA hydratase 1
Gene Symbol
ECH1
HGNC ID
HGNC:3149
ORF Size (aa)
987
ORF Size (bp)
987 bp
RefSeq ID
NM_001398
RefSeq Synonyms
NM_001398, BC017408, BC011792,
Species
human
UniGene ID
Hs.196176
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.