human DYRK3 shRNA silencing Adenovirus

Name 
Ad-h-DYRK3-shRNA
Cat No 
shADV-207483
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DYRK3.

shADV-207483
Ad-h-DYRK3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DYRK3 (dual specificity tyrosine phosphorylation regulated kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DYRK5; hYAK3-2; RED; REDK
Description (Vector)
DYRK3 product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
8444
Gene Name (Vector)
dual specificity tyrosine phosphorylation regulated kinase 3
Gene Symbol
DYRK3
HGNC ID
HGNC:3094
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_003582
RefSeq Synonyms
NM_003582, NM_001004023, BC015501,
Species
human
UniGene ID
Hs.164267

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.