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human DYNLT3 shRNA silencing Adenovirus

Name 
Ad-h-DYNLT3-shRNA
Cat No 
shADV-207476
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DYNLT3.

shADV-207476
Ad-h-DYNLT3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DYNLT3 (dynein light chain Tctex-type 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RP3; TCTE1L; TCTEX1L
Description (Vector)
DYNLT3 encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.
Gene ID
6990
Gene Name (Vector)
dynein light chain Tctex-type 3
Gene Symbol
DYNLT3
HGNC ID
HGNC:11694
ORF Size (aa)
351
RefSeq ID
NM_006520
RefSeq Synonyms
NM_006520, BC000968,
Species
human
UniGene ID
Hs.446392

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.