human DRD4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DRD4.
shADV-207329
Ad-h-DRD4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DRD4 (dopamine receptor D4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D4DR
Description (Vector)
DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Gene ID
1815
Gene Name (Vector)
dopamine receptor D4
Gene Symbol
DRD4
HGNC ID
HGNC:3025
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_000797
RefSeq Synonyms
NM_000797, BC172267,
Species
human
UniGene ID
Hs.99922
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.