human DPP3 shRNA silencing Adenovirus

Name 
Ad-h-DPP3-shRNA
Cat No 
shADV-207288
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DPP3.

shADV-207288
Ad-h-DPP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DPP3 (dipeptidyl peptidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; dipeptidyl peptidase 3; dipeptidyl peptidase III; DPP III; DPPIII; enkephalinase B
Description (eCommerce)
Dipeptidyl peptidase 3 (DPP3) cleaves and degrades of the opioid peptide enkephalin. DPP3 also cleaves Arg-Arg-beta-naphthylamide [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NY33].
Description (Vector)
DPP3 encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.
Gene ID
10072
Gene Name (eCommerce)
dipeptidyl peptidase 3
Gene Name (Vector)
dipeptidyl peptidase 3
Gene Symbol
DPP3
HGNC ID
HGNC:3008
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2214
ORF Size (bp)
2214 bp
Protein Name (eCommerce)
Dipeptidyl peptidase 3
RefSeq ID
NM_005700
RefSeq Synonyms
NM_130443, NM_005700, NM_001256670, BC024271, BC014038, BC007221, BC001446,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Dipeptidyl peptidase 3 (DPP3) cleaves and degrades of the opioid peptide enkephalin. DPP3 also cleaves Arg-Arg-beta-naphthylamide [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NY33].
UniGene ID
Hs.502914
UniProt ID (eCommerce)
Q9NY33

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.