human DOCK6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DOCK6.
shADV-207234
Ad-h-DOCK6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DOCK6 (dedicator of cytokinesis 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AOS2; ZIR1
Description (Vector)
DOCK6 encodes a member of the dedicator of cytokinesis (DOCK) family of atypical guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with small GTPases and are components of intracellular signaling networks. The encoded protein is a group C DOCK protein and plays a role in actin cytoskeletal reorganization by activating the Rho GTPases Cdc42 and Rac1. Mutations in this gene are associated with Adams-Oliver syndrome 2.
Gene ID
57572
Gene Name (Vector)
dedicator of cytokinesis 6
Gene Symbol
DOCK6
HGNC ID
HGNC:19189
ORF Size (aa)
6144
ORF Size (bp)
6144 bp
RefSeq ID
NM_020812
RefSeq Synonyms
NM_020812, BC146786,
Species
human
UniGene ID
Hs.591002
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.