human DFNB31 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human WHRN.
shADV-206901
Ad-h-DFNB31-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human WHRN (whirlin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CIP98; DFNB31; PDZD7B; USH2D; WI
Description (Vector)
DFNB31 is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
25861
Gene Name (Vector)
whirlin
Gene Symbol
WHRN
HGNC ID
HGNC:16361
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
RefSeq ID
NM_015404
RefSeq Synonyms
NM_015404, NM_001346890, NM_001173425, NM_001083885, BC142684, BC142614, BC136416,
Species
human
UniGene ID
Hs.93836
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.