human DEGS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DEGS1.
shADV-206860
Ad-h-DEGS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DEGS1 (delta 4-desaturase, sphingolipid 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DEGS; DEGS-1; Des-1; DES1; FADS7; MIG15; MLD
Description (Vector)
DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
Gene ID
8560
Gene Name (Vector)
delta 4-desaturase, sphingolipid 1
Gene Symbol
DEGS1
HGNC ID
HGNC:13709
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_003676
RefSeq Synonyms
NM_003676, NM_001321542, NM_001321541, BC000961,
Species
human
UniGene ID
Hs.299878
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.