human DEFA5 shRNA silencing Adenovirus

Name 
Ad-h-DEFA5-shRNA
Cat No 
shADV-206798
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human DEFA5.

shADV-206798
Ad-h-DEFA5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DEFA5 (defensin alpha 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DEF5; HD-5
Description (Vector)
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.
Gene ID
1670
Gene Name (Vector)
defensin alpha 5
Gene Symbol
DEFA5
HGNC ID
HGNC:2764
ORF Size (aa)
285
RefSeq ID
NM_021010
RefSeq Synonyms
NM_021010, BC107079, BC069690,
Species
human
UniGene ID
Hs.655233

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.