human DDOST shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DDOST.
shADV-206714
Ad-h-DDOST-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DDOST (dolichyl-diphosphooligosaccharide–protein glycosyltransferase non-catalytic subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGER1; CDG1R; OKSWcl45; OST; OST48; WBP1
Description (Vector)
DDOST encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Gene ID
1650
Gene Name (Vector)
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
Gene Symbol
DDOST
HGNC ID
HGNC:2728
ORF Size (aa)
1371
ORF Size (bp)
1371 bp
RefSeq ID
NM_005216
RefSeq Synonyms
NM_005216, BC002594,
Species
human
UniGene ID
Hs.523145
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.