human DCTN4 shRNA silencing Adenovirus

Name 
Ad-h-DCTN4-shRNA
Cat No 
shADV-206679
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DCTN4.

shADV-206679
Ad-h-DCTN4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DCTN4 (dynactin subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DYN4; dynactin 4 (p62); dynactin p62 subunit; dynactin subunit 4; dynactin subunit p62; P62
Description (eCommerce)
DCTN4/Dynactin p62 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. DCTN4/Dynactin p62 could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UJW0].
Gene ID
51164
Gene Name (eCommerce)
dynactin subunit 4
Gene Name (Vector)
dynactin subunit 4
Gene Symbol
DCTN4
HGNC ID
HGNC:15518
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1383
ORF Size (bp)
1383 bp
Protein Name (eCommerce)
Dynactin subunit 4
RefSeq ID
NM_016221
RefSeq Synonyms
NM_016221, NM_001135644, NM_001135643, BC026323,
Research Areas
Antigen Processing and Presentation,Cytoskeleton,Huntington's Disease,Immunology,Neurobiology,Neurodegeneration
Research Areas (Faceted)
immunology,cell_biology,neurobiology
Species
human
Target Sentence
DCTN4/Dynactin p62 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. DCTN4/Dynactin p62 could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9UJW0].
UniGene ID
Hs.675564
UniProt ID (eCommerce)
Q9UJW0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.