human DARS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DARS2.
shADV-206605
Ad-h-DARS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DARS2 (aspartyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASPRS; LBSL; MT-ASPRS
Description (Vector)
DARS2 belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
Gene ID
55157
Gene Name (Vector)
aspartyl-tRNA synthetase 2, mitochondrial
Gene Symbol
DARS2
HGNC ID
HGNC:25538
ORF Size (aa)
1938
ORF Size (bp)
1938 bp
RefSeq ID
NM_018122
RefSeq Synonyms
NM_018122, BC045173,
Species
human
UniGene ID
Hs.647707
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.