human DAP3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DAP3.
shADV-206589
Ad-h-DAP3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DAP3 (death associated protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bMRP-10; DAP-3; MRP-S29; MRPS29
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
Gene ID
7818
Gene Name (Vector)
death associated protein 3
Gene Symbol
DAP3
HGNC ID
HGNC:2673
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_004632
RefSeq Synonyms
NM_033657, NM_004632, NM_001199851, NM_001199850, NM_001199849, BC107488, BC107487,
Species
human
UniGene ID
Hs.516746
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.