human CYTH4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYTH4.
shADV-206549
Ad-h-CYTH4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYTH4 (cytohesin 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYT4; cytohesin-4; DJ63G5.1; PSCD4
Description (Vector)
CYTH4 is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar.
Gene ID
27128
Gene Name (Vector)
cytohesin 4
Gene Symbol
CYTH4
HGNC ID
HGNC:9505
ORF Size (aa)
1185
ORF Size (bp)
1185 bp
RefSeq ID
NM_013385
RefSeq Synonyms
NM_013385, NM_001318024, BC041161, BC017780,
Species
human
UniGene ID
Hs.170944
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.