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human CYP2C19 shRNA silencing Adenovirus

Name 
Ad-h-CYP2C19-shRNA
Cat No 
shADV-206484
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CYP2C19.

shADV-206484
Ad-h-CYP2C19-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP2C19 (cytochrome P450 family 2 subfamily C member 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19
Description (Vector)
CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Gene ID
1557
Gene Name (Vector)
cytochrome P450 family 2 subfamily C member 19
Gene Symbol
CYP2C19
HGNC ID
HGNC:2621
ORF Size (aa)
1470
ORF Size (bp)
1470 bp
RefSeq ID
NM_000769
RefSeq Synonyms
NM_000769, BC111846,
Species
human
UniGene ID
Hs.282409

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.