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human CYP2A6 shRNA silencing Adenovirus

Name 
Ad-h-CYP2A6-shRNA
Cat No 
shADV-206474
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CYP2A6.

shADV-206474
Ad-h-CYP2A6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP2A6 (cytochrome P450 family 2 subfamily A member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB
Description (Vector)
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
Gene ID
1548
Gene Name (Vector)
cytochrome P450 family 2 subfamily A member 6
Gene Symbol
CYP2A6
HGNC ID
HGNC:2610
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_000762
RefSeq Synonyms
NM_000762, BC096256, BC096255, BC096254, BC096253,
Species
human
UniGene ID
Hs.250615

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.