human CYP24A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYP24A1.
shADV-206462
Ad-h-CYP24A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP24A1 (cytochrome P450 family 24 subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CP24; CYP24; HCAI; HCINF1; P450-CC24
Description (Vector)
CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
1591
Gene Name (Vector)
cytochrome P450 family 24 subfamily A member 1
Gene Symbol
CYP24A1
HGNC ID
HGNC:2602
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_000782
RefSeq Synonyms
NM_001128915, NM_000782, BC109084, BC109083,
Species
human
UniGene ID
Hs.89663
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.