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human CYP19A1 shRNA silencing Adenovirus

Name 
Ad-h-CYP19A1-shRNA
Cat No 
shADV-206448
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CYP19A1.

shADV-206448
Ad-h-CYP19A1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP19A1 (cytochrome P450 family 19 subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Description (Vector)
CYP19A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Gene ID
1588
Gene Name (Vector)
cytochrome P450 family 19 subfamily A member 1
Gene Symbol
CYP19A1
HGNC ID
HGNC:2594
ORF Size (aa)
1512
ORF Size (bp)
1512 bp
RefSeq ID
NM_000103
RefSeq Synonyms
NM_031226, NM_001347256, NM_001347255, NM_001347254, NM_001347253, NM_001347252, NM_001347251, NM_001347250, NM_001347249, NM_001347248, NM_000103, BC107785, BC035959, BC035714, BC022896,
Species
human
UniGene ID
Hs.260074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.