human CYP11A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CYP11A1.
shADV-206441
Ad-h-CYP11A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CYP11A1 (cytochrome P450 family 11 subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYP11A; CYPXIA1; P450SCC
Description (Vector)
CYP11A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
Gene ID
1583
Gene Name (Vector)
cytochrome P450 family 11 subfamily A member 1
Gene Symbol
CYP11A1
HGNC ID
HGNC:2590
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_000781
RefSeq Synonyms
NM_001099773, NM_000781, BC032329,
Species
human
UniGene ID
Hs.303980
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.