human CXORF15 shRNA silencing Adenovirus

Name 
Ad-h-CXORF15-shRNA
Cat No 
shADV-206350
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TXLNG.

shADV-206350
Ad-h-CXORF15-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TXLNG (taxilin gamma). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CXorf15; ELRG; environmental lipopolysaccharide-responding gene protein; environmental LPS-responding; factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription; factor inhibiting ATF4-mediated transcription; FIAT; gamma-taxilin; lipopolysaccharide specific response-5 protein; lipopolysaccharide-specific response protein 5; LSR5; TXLNGX
Description (eCommerce)
Gamma-Taxilin is a member of the taxilin family. Gamma-taxilin binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. Gamma-taxilin is up-regulated by lipopolysaccharide may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual [taken from NCBI Entrez Gene (Gene ID: 55787)].
Description (Vector)
TXLNG encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. TXLNG is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
55787
Gene Name (eCommerce)
taxilin gamma
Gene Name (Vector)
taxilin gamma
Gene Symbol
TXLNG
HGNC ID
HGNC:18578
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
Protein Name (eCommerce)
Gamma-taxilin
RefSeq ID
NM_018360
RefSeq Synonyms
NM_018360, NM_001168683, BC101576, BC101572,
Research Areas
Cell Cycle,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Gamma-Taxilin is a member of the taxilin family. Gamma-taxilin binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. Gamma-taxilin is up-regulated by lipopolysaccharide may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual [taken from NCBI Entrez Gene (Gene ID: 55787)].
UniGene ID
Hs.555961
UniProt ID (eCommerce)
Q9NUQ3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.