human CXCR3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CXCR3.
shADV-206343
Ad-h-CXCR3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CXCR3 (C-X-C motif chemokine receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR
Description (Vector)
CXCR3 encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
Gene ID
2833
Gene Name (Vector)
C-X-C motif chemokine receptor 3
Gene Symbol
CXCR3
HGNC ID
HGNC:4540
ORF Size (aa)
1107
ORF Size (bp)
1107 bp
RefSeq ID
NM_001504
RefSeq Synonyms
NM_001504, NM_001142797, BC034403,
Species
human
UniGene ID
Hs.198252
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.