human CRX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CRX.
shADV-206041
Ad-h-CRX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CRX (cone-rod homeobox). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CORD2; CRD; LCA7; OTX3
Description (Vector)
CRX is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Gene ID
1406
Gene Name (Vector)
cone-rod homeobox
Gene Symbol
CRX
HGNC ID
HGNC:2383
ORF Size (aa)
900
ORF Size (bp)
900 bp
RefSeq ID
NM_000554
RefSeq Synonyms
NM_000554, BC053672, BC016664,
Species
human
UniGene ID
Hs.639114
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.