human COX4I1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human COX4I1.
shADV-205826
Ad-h-COX4I1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human COX4I1 (cytochrome c oxidase subunit 4I1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COX IV-1; COX4; COX4-1; COXIV; COXIV-1; cytochrome c oxidase polypeptide IV; cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; Cytochrome c oxidase subunit IV isoform 1
Description (eCommerce)
COX4 (cytochrome c oxidase, subunit IV isoform 1) is one of 13 subunits of the multiprotein COX (cytochrome oxidase) complex which functions as the terminal enzyme in the mitochondrial respiratory chain.
Description (Vector)
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Gene ID
1327
Gene Name (eCommerce)
cytochrome c oxidase subunit 4I1
Gene Name (Vector)
cytochrome c oxidase subunit 4I1
Gene Symbol
COX4I1
HGNC ID
HGNC:2265
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
510
ORF Size (bp)
510 bp
Protein Name (eCommerce)
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
RefSeq ID
NM_001861
RefSeq Synonyms
NM_001861, NM_001318802, NM_001318797, NM_001318794, NM_001318788, NM_001318786, BC062437, BC047869, BC021236, BC008704,
Research Areas
Alzheimer's Disease,Cardiology,Cardiovascular,Huntington's Disease,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease
Research Areas (Faceted)
neurobiology,cardiovascular,metabolism,cell_biology
Species
human
Target Sentence
COX4 (cytochrome c oxidase, subunit IV isoform 1) is one of 13 subunits of the multiprotein COX (cytochrome oxidase) complex which functions as the terminal enzyme in the mitochondrial respiratory chain.
UniGene ID
Hs.433419
UniProt ID (eCommerce)
P13073
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.