human CNNM2 shRNA silencing Adenovirus

Name
Ad-h-CNNM2-shRNA

Cat No
shADV-205598

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CNNM2.

shADV-205598

Ad-h-CNNM2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

ACDP2; HOMG6; HOMGSMR

Description (Vector)

CNNM2 encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

54805

Gene Name (Vector)

cyclin and CBS domain divalent metal cation transport mediator 2

Gene Symbol

CNNM2

HGNC ID

HGNC:103

ORF Size (aa)

1659

ORF Size (bp)

1659 bp

RefSeq ID

NM_017649

RefSeq Synonyms

NM_199077, NM_199076, NM_017649, BC021222,

Species

human

UniGene ID

Hs.657970

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.