human CLK1 shRNA silencing Adenovirus

Name 
Ad-h-CLK1-shRNA
Cat No 
shADV-205466
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLK1.

shADV-205466
Ad-h-CLK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLK1 (CDC like kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLK; CLK/STY; STY
Description (Vector)
CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
1195
Gene Name (Vector)
CDC like kinase 1
Gene Symbol
CLK1
HGNC ID
HGNC:2068
ORF Size (aa)
1455
ORF Size (bp)
1455 bp
RefSeq ID
NM_004071
RefSeq Synonyms
NM_004071, NM_001162407, BC031549,
Species
human
UniGene ID
Hs.433732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.