human CLDN5 shRNA silencing Adenovirus

Name
Ad-h-CLDN5-shRNA

Cat No
shADV-205383

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLDN5.

shADV-205383

Ad-h-CLDN5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLDN5 (claudin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AWAL; BEC1; CPETRL1; TMVCF

Description (Vector)

CLDN5 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene ID

7122

Gene Name (Vector)

claudin 5

Gene Symbol

CLDN5

HGNC ID

HGNC:2047

ORF Size (aa)

657

ORF Size (bp)

657 bp

RefSeq ID

NM_003277

RefSeq Synonyms

NM_003277, NM_001130861, BC032363, BC019290, BC002404,

Species

human

UniGene ID

Hs.505337

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.