human CLCA2 shRNA silencing Adenovirus

Name 
Ad-h-CLCA2-shRNA
Cat No 
shADV-205339
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLCA2.

shADV-205339
Ad-h-CLCA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLCA2 (chloride channel accessory 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CACC; CaCC-3; CACC3; CLCRG2
Description (Vector)
CLCA2 belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
Gene ID
9635
Gene Name (Vector)
chloride channel accessory 2
Gene Symbol
CLCA2
HGNC ID
HGNC:2016
ORF Size (aa)
2832
ORF Size (bp)
2832 bp
RefSeq ID
NM_006536
RefSeq Synonyms
NM_006536, BC041096,
Species
human
UniGene ID
Hs.241551

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.