human CHRM1 shRNA silencing Adenovirus

Name 
Ad-h-CHRM1-shRNA
Cat No 
shADV-205196
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CHRM1.

shADV-205196
Ad-h-CHRM1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CHRM1 (cholinergic receptor muscarinic 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HM1; M1; M1R
Description (Vector)
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Gene ID
1128
Gene Name (Vector)
cholinergic receptor muscarinic 1
Gene Symbol
CHRM1
HGNC ID
HGNC:1950
ORF Size (aa)
1383
ORF Size (bp)
1383 bp
RefSeq ID
NM_000738
RefSeq Synonyms
NM_000738, BC022984, BC007740,
Species
human
UniGene ID
Hs.632119

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.