human CHRDL2 shRNA silencing Adenovirus

Name 
Ad-h-CHRDL2-shRNA
Cat No 
shADV-205191
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CHRDL2.

shADV-205191
Ad-h-CHRDL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CHRDL2 (chordin like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BNF1; BNF-1; breast tumor novel factor 1; CHL2; chordin-like protein 2; chordin-related protein 2
Description (eCommerce)
BNF1 (breast tumor novel factor 1) was first identified as an mRNA differentially expressed between vascularized tumor breast tissue and adjacent normal tissue. BNF1 overexpression has been found in breast, lung, and colon tumors. BNF1 has also been identified as a differentially expressed mRNA during myoblast and osteoblast differentiation. BNF1 contains chordin-like cysteine-rich repeats and is part of a family of secreted proteins that associate with members of the TGF-beta superfamily. BNF1 displays an extensive and complex pattern of alternative splicing that results in several isoforms expressed in distinct tissue.
Gene ID
25884
Gene Name (eCommerce)
chordin like 2
Gene Name (Vector)
chordin like 2
Gene Symbol
CHRDL2
HGNC ID
HGNC:24168
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1353
ORF Size (bp)
1353 bp
Protein Name (eCommerce)
Chordin-like protein 2
RefSeq ID
NM_015424
RefSeq Synonyms
NM_015424, NM_001304417, NM_001304416, NM_001304415, NM_001304391, NM_001304390, NM_001278473, BC153100, BC142623, BC141564,
Research Areas
Mitochondrion,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
BNF1 (breast tumor novel factor 1) was first identified as an mRNA differentially expressed between vascularized tumor breast tissue and adjacent normal tissue. BNF1 overexpression has been found in breast, lung, and colon tumors. BNF1 has also been identified as a differentially expressed mRNA during myoblast and osteoblast differentiation. BNF1 contains chordin-like cysteine-rich repeats and is part of a family of secreted proteins that associate with members of the TGF-beta superfamily. BNF1 displays an extensive and complex pattern of alternative splicing that results in several isoforms expressed in distinct tissue.
UniGene ID
Hs.432379
UniProt ID (eCommerce)
Q6WN34

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.