human CGGBP1 shRNA silencing Adenovirus

Name
Ad-h-CGGBP1-shRNA

Cat No
shADV-205075

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human CGGBP1.

shADV-205075

Ad-h-CGGBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CGGBP1 (CGG triplet repeat binding protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

80

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

20 kDa CGG-binding protein; CGG triplet repeat-binding protein 1; CGG-binding protein 1; CGGBP; p20-CGG binding protein; p20-CGGBP; p20-CGGBP DNA-binding protein

Description (eCommerce)

CGG triplet repeat binding protein 1 (CGGBP1) binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. CGGBP1 may play a role in regulating FMR1 promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14789].

Description (Vector)

CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.(supplied by OMIM, Mar 2008)

Gene ID

8545

Gene Name (eCommerce)

CGG triplet repeat binding protein 1

Gene Name (Vector)

CGG triplet repeat binding protein 1

Gene Symbol

CGGBP1

HGNC ID

HGNC:1888

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

504

ORF Size (bp)

504 bp

Protein Name (eCommerce)

CGG triplet repeat-binding protein 1

RefSeq ID

NM_003663

RefSeq Synonyms

NM_003663, NM_001195308, NM_001008390, BC052980,

Research Areas

Transcription Factor/Regulator

Research Areas (Faceted)

cell_biology,transcription_translation

Species

human

Target Sentence

CGG triplet repeat binding protein 1 (CGGBP1) binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. CGGBP1 may play a role in regulating FMR1 promoter [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14789].

UniGene ID

Hs.444818

UniProt ID (eCommerce)

Q9UFW8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.