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human CFHR4 shRNA silencing Adenovirus

Name 
Ad-h-CFHR4-shRNA
Cat No 
shADV-205049
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CFHR4.

shADV-205049
Ad-h-CFHR4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CFHR4 (complement factor H related 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CFHL4; FHR-4; FHR4
Description (Vector)
CFHR4 is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
Gene ID
10877
Gene Name (Vector)
complement factor H related 4
Gene Symbol
CFHR4
HGNC ID
HGNC:16979
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_006684
RefSeq Synonyms
NM_006684, NM_001201551, NM_001201550, BC074957,
Species
human
UniGene ID
Hs.710100

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.