human CENPH shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CENPH.
shADV-204956
Ad-h-CENPH-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CENPH (centromere protein H). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.
Gene ID
64946
Gene Name (Vector)
centromere protein H
Gene Symbol
CENPH
HGNC ID
HGNC:17268
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_022909
RefSeq Synonyms
NM_022909, BC015355, BC012024,
Species
human
UniGene ID
Hs.631967
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.