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human CEL shRNA silencing Adenovirus

Name 
Ad-h-CEL-shRNA
Cat No 
shADV-204947
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CEL.

shADV-204947
Ad-h-CEL-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CEL (carboxyl ester lipase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAL; BSDL; BSSL; CEase; CELL; FAP; FAPP; LIPA; MODY8
Description (Vector)
CEL is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
Gene ID
1056
Gene Name (Vector)
carboxyl ester lipase
Gene Symbol
CEL
HGNC ID
HGNC:1848
ORF Size (aa)
2169
ORF Size (bp)
2169 bp
RefSeq ID
NM_001807
RefSeq Synonyms
NM_001807, BC042510,
Species
human
UniGene ID
Hs.533258

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.