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human CEACAM5 shRNA silencing Adenovirus

Name 
Ad-h-CEACAM5-shRNA
Cat No 
shADV-204931
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CEACAM5.

shADV-204931
Ad-h-CEACAM5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CEACAM5 (carcinoembryonic antigen related cell adhesion molecule 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CEA; CD66e
Description (eCommerce)
Carcinoembryonic antigen related cell adhesion molecules 1 and 5 (CEACAM1 and CEACAM5) are members of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, CEACAM5 may regulate differentiation, apoptosis, and cell polarity.
Description (Vector)
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).(supplied by OMIM, Oct 2009)
Gene ID
1048
Gene Name (eCommerce)
carcinoembryonic antigen related cell adhesion molecule 5
Gene Name (Vector)
carcinoembryonic antigen related cell adhesion molecule 5
Gene Symbol
CEACAM5
HGNC ID
HGNC:1817
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2109
ORF Size (bp)
2109 bp
Protein Name (eCommerce)
Carcinoembryonic antigen-related cell adhesion molecule 5
RefSeq ID
NM_004363
RefSeq Synonyms
NM_004363, NM_001308398, NM_001291484, BC034671,
Research Areas
Immunology,Immuno-Oncology,Signal Transduction
Research Areas (Faceted)
immunology,immuno_oncology,signal_transduction
Species
human
Target Sentence
Carcinoembryonic antigen related cell adhesion molecules 1 and 5 (CEACAM1 and CEACAM5) are members of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. CEACAM1 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, CEACAM5 may regulate differentiation, apoptosis, and cell polarity.
UniGene ID
Hs.709196
UniProt ID (eCommerce)
P06731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.