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human CDX2 shRNA silencing Adenovirus

Name 
Ad-h-CDX2-shRNA
Cat No 
shADV-204907
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CDX2.

shADV-204907
Ad-h-CDX2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDX2 (caudal type homeobox 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2/AS; CDX3; CDX-3; homeobox protein CDX-2; homeobox protein miniCDX2
Description (eCommerce)
CDX is a caudal-related protein (Cdx) and member of the homeobox class of genes. Homeobox genes are a large family of transcription factors that play an important role in mesoderm development. CDX2 is one of three human homologs that functions in posterior structure development and intestinal epithelial development. CDX2 is a transactivator of several intestine-specific genes such as isomaltase, lactase, carbonic anhydrase, MUC2, and others. CDX2 may function as a tumor suppressor in the colon.
Description (Vector)
CDX2 is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Gene ID
1045
Gene Name (eCommerce)
caudal type homeobox 2
Gene Name (Vector)
caudal type homeobox 2
Gene Symbol
CDX2
HGNC ID
HGNC:1806
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
942
ORF Size (bp)
942 bp
Protein Name (eCommerce)
Homeobox protein CDX-2
RefSeq ID
NM_001265
RefSeq Synonyms
NM_001265, BC014461,
Research Areas
Lysosomal Transport,Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
CDX is a caudal-related protein (Cdx) and member of the homeobox class of genes. Homeobox genes are a large family of transcription factors that play an important role in mesoderm development. CDX2 is one of three human homologs that functions in posterior structure development and intestinal epithelial development. CDX2 is a transactivator of several intestine-specific genes such as isomaltase, lactase, carbonic anhydrase, MUC2, and others. CDX2 may function as a tumor suppressor in the colon.
UniGene ID
Hs.174249
UniProt ID (eCommerce)
Q99626

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.