human CDS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDS2.
shADV-204901
Ad-h-CDS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDS2 (CDP-diacylglycerol synthase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
Gene ID
8760
Gene Name (Vector)
CDP-diacylglycerol synthase 2
Gene Symbol
CDS2
HGNC ID
HGNC:1801
ORF Size (aa)
1338
ORF Size (bp)
1338 bp
RefSeq ID
NM_003818
RefSeq Synonyms
NM_003818, BC025751,
Species
human
UniGene ID
Hs.472027
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.