human CDKN2C shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-204884
Availability:
3-5 weeks
Name:
Ad-h-CDKN2C-shRNA
This is an Adenovirus expressing shRNA for silencing of Human CDKN2C.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDKN2C
- Gene Name
- cyclin dependent kinase inhibitor 2C
- Gene ID
- 1031
- Gene Synonyms
- INK4C; p18; p18-INK4C
- ORF Size
- 507 bp
- RefSeq#
- NM_001262
- Gene Description
- CDKN2C is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
- UniGene ID
- Hs.716664
- HGNC ID
- HGNC:1789
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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