human CDH8 shRNA silencing Adenovirus

Name 
Ad-h-CDH8-shRNA
Cat No 
shADV-204833
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CDH8.

shADV-204833
Ad-h-CDH8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDH8 (cadherin 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Nbla04261
Description (Vector)
CDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Gene ID
1006
Gene Name (Vector)
cadherin 8
Gene Symbol
CDH8
HGNC ID
HGNC:1767
ORF Size (aa)
2400
ORF Size (bp)
2400 bp
RefSeq ID
NM_001796
RefSeq Synonyms
NM_001796, BC113416,
Species
human
UniGene ID
Hs.368322

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.